Vertebral fractures are usually the first to occur in osteoporosis, provide indisputable evidence of reduced bone strength, and are frequently a harbinger of further vertebral and nonvertebral fracture. Radiologists are best placed to draw attention to the presence of vertebral fractures, most of which are clinically silent. Magnetic resonance imaging supplemented if necessary by computed tomography is usually sufficient to enable distinction between osteoporotic and nonosteoporotic vertebral fracture, without a need for percutaneous biopsy.
aDepartment of Diagnostic Radiology and Organ Imaging, Chinese University of Hong Kong, Prince of Wales Hospital, Ngan Shing Street, Shatin, New Territories, Hong Kong
bDepartment of Radiology, University of Foggia, San Giovanni Rotondo, Viale L. Pinto, 71100 Foggia, Italy
cScientific Institute 'Casa Sollievo della Sofferenza' Hospital, San Giovanni Rotondo 71013, Italy